Dr Månsson's Research Lab
Kristoffer N T Månsson, PhD
Things we like to do
Moment-to-moment variability in neural response as a predictor of patients outcome after treatment
Temporal dynamics in the treatment of social anxiety disorder
Cellular protection and biological aging in social anxiety disordered patients receiving cognitive-behavioral therapy (CBT)
Investigate rapid brain plasticity using structural magnetic resonance imaging
Developing an internet-based tool for clinicians
Latest news from the lab
Website launch party!
2020.04.01 The website launch party was held in the canteen at the Max Planck Institute for Human Development, Berlin, Germany.
Awarded the best talk at the Alpine Brain Imaging Meeting
2020.01.16 I got an award fot the best talk at the Alpine Brain Imaging Meeting in Champéry, Switzerland. See you next year! More info, click here!
Cellular protection after psychological treatment
2019.12.19 New paper out! Improvement in indices of cellular protection after psychological treatment for social anxiety disorder. The article is available for free, click here!
An academic dream team
Kristoffer N T Månsson, PhD
Principal Investigator
Postdoctoral fellow (2019-2020)
Study Director, Psychiatry Research School
Samir El Alaoui, PhD
Research coordinator (post doc), Centre for Psychiatry Research, Karolinska Institutet
Dr Samir El Alaoui is a clinical psychologist with several years of clinical and research experience at the Internet Psychiatry Clinic in Stockholm, Sweden. He received his PhD in 2016 on the evaluation of internet-based CBT for social anxiety, studying its effectiveness, outcome predictors and health economics when implemented in routine psychiatric care. He has also been involved in creating Sweden’s national quality registry for internet-based psychological treatments (SibeR). Currently, Dr El Alaoui is coordinating a research project including fMRI to predict the outcome of CBT in adults with depression, insomnia or health anxiety disorder.
Amir Manzouri, MSc
Research engineer, Department of Psychology, Stockholm University; Centre for Psychiatry Research, Karolinska Institutet
Amir studied medical imaging at the Royal Institute of Technology in Stockholm and have been working with neuroimaging methods as a research engineer since 2010. Amir have been involved in research on Alzheimer’s disease, gender identity, emotion, stress and anxiety disorders. Amir have extensive experience with data collection (e.g., magnetic resonance imaging, MRI scanning), and expertise in data pre- and post-processing, higher level statistical analyses on functional MRI data, e.g., psycho-physiological interactions (PPI), partial least squares (PLS), support vector machines (SVM), and independent component analysis (ICA). Moreover, Amir also have extensive expertise in structural MRI data analysis, e.g., FreeSurfer, AFNI, BrainVoyager, and voxel based morphometry (VBM), and tract-based spatial statistics (TBSS).
Students and internships (alumni)
Supervision (bachelor and master level)
Extended network and collaborations
A selection of ongoing collaborations with principal investigators
National collaborations
International collaborations
Scientific publications
Highlighted publications
Preprints and articles in press
Månsson, K. N. T., Cortes, D. S., Manzouri, A., Hau, S., Fischer, H. (2019) Viewing pictures triggers rapid morphological enlargement in the human visual cortex. Cerebral Cortex. In press: https://doi.org/10.1093/cercor/bhz131
Peer-reviewed published articles
24. Kraepelien, M., Schibbye, R., Månsson K. N. T., Sundström, C., Riggare, S., Andersson, G., Lindefors, N., Svenningsson, P., & Kaldo, V. (2020) Individually tailored internet-based cognitive-behavioral therapy for daily functioning in patients with Parkinson’s disease: a randomized controlled trial. Journal of Parkinson's Disease, In press
23. Månsson, K. N. T., Lindqvist, D., Yang, L., Svanborg, C., Isung, J., Nilsonne, G., Bergman Nordgren, L., El Alaoui, S., Hedman-Lagerlöf, E., Kraepelien, M., Högström, J., Andersson, G., Boraxbekk, CJ., Fischer, H., Lavebratt, C., Wolkowitz, O., Furmark, T. (2019) Improvement in indices of cellular protection after psychological treatment for social anxiety disorder. Translational Psychiatry, 9, 340. https://doi.org/10.1038/s41398-019-0668-2
22. Hjorth, O.R., Frick, A., Gingnell, M., Hoppe, J.M., Faria, V., Hultberg, S., Alaie, I., Månsson, K.N.T., Wahlstedt, K., Jonasson, M., Lubberink, M., Antoni, G., Fredrikson, M., Furmark, T. (2019) Expression and co-expression of serotonin and dopamine transporters in social anxiety disorder: a multitracer positron emission tomography study. Mol. Psychiatry. doi:10.1038/s41380-019-0618-7
21. Han, L. K. M., Verhoeven, J. E., Tyrka, A. R., Penninx, B. W. J. H., Wolkowitz, O. M., Månsson, K. N. T., Lindqvist, D., Boks, M. P., Révész, D., Mellon., H. S., Picard, M. (2019). Accelerating research on biological aging and mental health: Current challenges and future directions. Psychoneuroendocrinology, 106, 293–311. doi: 10.1016/j.psyneuen.2019.04.004
20. Rozental, A., Kottorp, A., Forsström, D., Månsson, K. N. T., Boettcher, J., Andersson, G., Furmark, T., & Carlbring, P. (in press). The Negative Effects Questionnaire: Psychometric properties of an instrument for assessing negative effects in psychological treatments. Behavioural and Cognitive Psychotherapy. doi:10.1017/S1352465819000018
19. Frick, A. & Månsson, K. N. T. (2018) Brain changes in social anxiety disorder run in the family. EBioMedicine, 36, 5-6, https://doi.org/10.1016/j.ebiom.2018.09.009
18. Ivanov, V. Z., Enander, J., Mataix-Cols, D., Serlachius, E., Lichtenstein, P., Månsson, K. N. T., Andersson, G., Tolin, D., Flygare, O., & Rück, C. (2018). Enhancing group cognitive-behavior therapy for hoarding disorder with between-session Internet-based clinician support: a feasibility study. Journal of Clinical Psychology, 1-14. doi: 10.1002/jclp.22589
17. Goodwin, G. M., Holmes, E. A., Andersson, E., Browning, M., Jones, A., Lass-Hennemann, J., Månsson, K. N. T., Moessnang, C., Salemink, E., Sanchez, A., van Zutphen, L., Visser, R. M. (2018). From neuroscience to evidence based psychological treatments - The promise and the challenge, ECNP March 2016, Nice, France. European Neuropsychopharmacology, 28(2), 317-333. doi:https://doi.org/10.1016/j.euroneuro.2017.10.036
16. Lenhard, F., Sauer, S., Andersson, E., Månsson, K. N., Mataix-Cols, D., Ruck, C., & Serlachius, E. (2017). Prediction of outcome in internet-delivered cognitive behaviour therapy for paediatric obsessive-compulsive disorder: A machine learning approach. Int J Methods Psychiatr Res. doi:10.1002/mpr.1576
15. Faria, V., Gingnell, M., Hoppe, J. M., Hjorth, O., Alaie, I., Frick, A., Hultberg, S., Wahlstedt, K., Engman, J., Månsson, K. N. T., Carlbring, P., Andersson, G., Reis, M., Larsson, E.-M., Fredrikson, M., & Furmark, T. (2017). Do You Believe It? Verbal Suggestions Influence the Clinical and Neural Effects of Escitalopram in Social Anxiety Disorder: A Randomized Trial. EBioMedicine, 24, 179-188. doi:10.1016/j.ebiom.2017.09.031
14. Bas-Hoogendam, J. M., van Steenbergen, H., Nienke Pannekoek, J., Fouche, J.-P., Lochner, C., Hattingh, C. J., Cremers, H. R., Furmark, T., Månsson, K. N. T., Frick, A., Engman, J., Boraxbekk, C.-J., Carlbring, P., Andersson, G., Fredrikson, M., Straube, T., Peterburs, J., Klumpp, H., Phan, K. L., Roelofs, K., Veltman, D. J., van Tol, M.-J., Stein, D. J., & van der Wee, N. J. A. (2017). Voxel-based morphometry multi-center mega-analysis of brain structure in social anxiety disorder. NeuroImage: Clinical, 16, 678-688. doi:10.1016/j.nicl.2017.08.001
13. Månsson, K. N. T., Klintmalm, H., Nordqvist, R., & Andersson, G. (2017). Conventional cognitive behaviour therapy facilitated by an internet-based support system: a feasibility study at a psychiatric outpatient clinic. JMIR Research Protocols, 6:e158.
10. Månsson, K. N. T., Salami, A., Carlbring, P., Boraxbekk, C.-J., Andersson, G., & Furmark, T. (2017). Structural but not functional neuroplasticity one year after effective cognitive behaviour therapy for social anxiety disorder. Behavioural Brain Research, 318, 45–51.
9. Månsson, K. N. T., Salami, A., Frick, A., Carlbring, P., Andersson, G., Furmark, T., Boraxbekk, C. J. (2016). Neuroplasticity in response to cognitive behavior therapy for social anxiety disorder. Translational Psychiatry, 6:e727. doi:10.1038/tp.2015.218
8. Brännström, K. J., Öberg, M., Ingo, E., Månsson, K. N. T., Andersson, G., Lunner, T., & Laplante-Lévesque, A. (2016). The initial evaluation of an internet-based support system for audiologists and first-time hearing aid clients. Internet Interventions, 4, 82-91.
7. Månsson, K. N. T., Frick, A., Boraxbekk, C. J., Marquand, A. F., Williams, S. C., Carlbring, P., Andersson, G., & Furmark, T. (2015). Predicting long-term outcome of cognitive behavior therapy for social anxiety disorder using fMRI and support vector machines. Translational Psychiatry, 5:e530. doi:10.1038/tp.2015.22
6. Nilsonne, G., Tamm, S., Månsson, K. N. T., Åkerstedt, T., & Lekander, M. (2015). Leukocyte telomere length and hippocampus volume: a meta-analysis. F1000Research, 4:1073.
5. Tulbure, B. T., Szentagotai, A., David, O., Stefan, S., Månsson, K. N. T., David, D., & Andersson, G. (2015). Internet-delivered cognitive-behavioral therapy for social anxiety disorder in Romania: a randomized controlled trial. PloS ONE, 10(5):e0123997.
4. Brännström, K. J., Öberg, M., Ingo, E., Månsson, K. N. T., Andersson, G., Lunner, T., & Laplante-Lévesque, A. (2015). The process of developing an internet-based support system for audiologists and first-time hearing aid clients. American Journal of Audiology, 24, 320-324.
3. Månsson, K. N. T., Carlbring, P., Frick, A., Engman, J., Olsson, C.-J., Bodlund, O., Furmark, T., & Andersson, G. (2013). Altered neural correlates of affective processing after internet-delivered cognitive behavior therapy for social anxiety disorder. Psychiatry Research, 214(3), 229-37.
2. Månsson, K. N. T., Skagius Ruiz, E., Gervind, E., Dahlin, M., & Andersson, G. (2013). Development and initial evaluation of an Internet-based support system for face-to-face cognitive behavior therapy: a proof of concept study. J Med Internet Res., 15(12):e280.
1. Tulbure, B. T., Månsson, K. N. T., & Andersson, G. (2012). Internet treatment for social anxiety disorder in Romania: Study protocol for a randomized controlled trial. Trials, 12:302.
Funding sources
We are grateful for the generous support provided by the
Vetenskapsrådet
International post doc, 3 year funding: "Improving psychological treatments for anxiety disorders by investigating the temporal dynamics of brain’s neural responses"
Swedish Brain Foundation
Funding provided 2016, 2018, and 2019, in research projects in collaboration with Professor Tomas Furmark (main applicant).
All the other helpful sources
Psykiatrifonden (2015), Carlo Perris Minnesfond and the ICCP stipend (2017, 2019), Centre for psychiatry research (2014, 2015), PRIMAs Forskningsfond (2013), Capio Forskningsstiftelse (2011, 2012).
Media presence
Our research in the media:
Scientific American
"Cognitive-behavioral therapy improved both symptoms and markers of senescence in people with anxiety" Click here to go to the Scientific American magazine
Forskning & Framsteg
Rätt hjärnmönster för en lyckad terapi. En undersökning av hjärnans aktivitet avslöjar hur patienten kommer att svara på behandling med KBT. Klicka här för att läsa artikeln
Psykologtidningen
Biologi och psykologi i förening kan bidra till effektivare och mer individanpassad psykologisk behandling. Ladda hem artikeln här
@neuronsson
Contact details
Kristoffer Månsson
kristoffer.mansson@
Phone
+46 070 580 3267
Copyright 2020